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Excitatory neuron-prone prion propagation and excitatory neuronal loss in prion-infected mice

The accumulation of a disease-specific isoform of prion protein (PrPSc) and histopathological lesions, such as neuronal loss, are unevenly distributed in the brains of humans and animals affected with prion diseases. This distribution varies depending on the diseases and/or the combinations of prion...

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Bibliografiske detaljer
Principais autores: Temuulen Erdenebat, Yusuke Komatsu, Nozomi Uwamori, Misaki Tanaka, Takashi Hoshika, Takeshi Yamasaki, Ayano Shimakura, Akio Suzuki, Toyotaka Sato, Motohiro Horiuchi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-12-01
Serier:Frontiers in Molecular Neuroscience
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1498142/full
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