Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice.

<h4>Background</h4>Telomeres are essential to maintain chromosomal stability. Cells derived from mice lacking telomerase RNA component (mTERC-/- mice) display elevated telomere-mediated chromosome instability. Age-dependent telomere shortening and associated chromosome instability reduce the capacit...

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Hlavní autoři:	Rabindra N Bhattacharjee, Birendranath Banerjee, Shizuo Akira, M Prakash Hande
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2010-07-01
Edice:	PLoS ONE
On-line přístup:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20686699/?tool=EBI
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