Distinct reduction in relative microglial glucose uptake compared to astrocytes and neurons upon isolation from the brain environment

IntroductionMicroglial energy metabolism has gained attention for the treatment of neurodegenerative diseases. In vitro methods provide important insights; however, it remains unclear whether the metabolism of highly motile microglia is preserved outside their regular environment. Therefore, we dire...

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Auteurs principaux:	Sebastian T. Kunte, Johannes Gnörich, Philipp Beumers, Laura M. Bartos, Stephan Wagner, Karin Wind-Mark, Adrien Holzgreve, Dennis Pötter, Rudolf A. Werner, Sibylle Ziegler, Nathalie L. Albert, Alessio Colombo, Sabina Tahirovic, Matthias Brendel
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2025-09-01
Collection:	Frontiers in Cellular Neuroscience
Sujets:	microglia glucose uptake in vivo in vitro scRadiotracing
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fncel.2025.1572431/full
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