Serum and cerebrospinal fluid neurofilament light chain and glial fibrillary acid protein levels in early and advanced stages of cerebral amyloid Angiopathy

Abstract Background Neurofilament light chain (NFL) is a biomarker for neuroaxonal damage and glial fibrillary acidic protein (GFAP) for reactive astrocytosis. Both processes occur in cerebral amyloid angiopathy (CAA), but studies investigating the potential of NFL and GFAP as markers for CAA are la...

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Главные авторы:	Ingeborg Rasing, Sabine Voigt, Emma A. Koemans, Anna M. de Kort, Thijs W. van Harten, Ellis S. van Etten, Erik W. van Zwet, Erik Stoops, Cindy Francois, H. Bea Kuiperij, Catharina J.M. Klijn, Floris H.B.M. Schreuder, Louise van der Weerd, Matthias J.P. van Osch, Marianne A.A. van Walderveen, Marcel M. Verbeek, Gisela M. Terwindt, Marieke J.H. Wermer
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2024-04-01
Серии:	Alzheimer’s Research & Therapy
Предметы:	Cerebral amyloid angiopathy Neurofilament light chain (NFL) Glial fibrillary acidic protein (GFAP) CAA CSVD score MoCA
Online-ссылка:	https://doi.org/10.1186/s13195-024-01457-0
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