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The Effect of Absorption-Enhancement and the Mechanism of the PAMAM Dendrimer on Poorly Absorbable Drugs

The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the mechanism of PAMAM dendrimers with generation 0 to generation 3 (G0–G3) and concentrations (0.1–1.0%) on the pulmonary absorption of m...

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Autori principali: Juan Lu, Nannan Li, Yaochun Gao, Nan Li, Yifei Guo, Haitao Liu, Xi Chen, Chunyan Zhu, Zhengqi Dong, Akira Yamamoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2018-08-01
Serie:Molecules
Soggetti:
PAMAM dendrimer
fluorescein isothiocyanate-dextrans
absorption-enhancement
mechanism
Accesso online:http://www.mdpi.com/1420-3049/23/8/2001
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