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Senescent Astrocytes: A New Player in Brain Aging and Cognitive Decline

Astrocytes are critical for maintaining brain homeostasis through metabolic support, neurotransmitter regulation, and blood–brain barrier integrity. In the aging brain and neurodegenerative conditions, astrocytes undergo functional and morphological changes that culminate in a state of cellular sene...

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Autori principali: Bruna Pessoa, Lívia de Sá Hayashide, Gustavo Dias, Bruno Pontes, Rafael Serafim Pinto, Luan Pereira Diniz
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2026-01-01
Serie:Brain Sciences
Soggetti:
astrocyte senescence
neuroinflammation
brain aging
synaptic dysfunction
neurodegeneration
mitochondrial dysfunction
Accesso online:https://www.mdpi.com/2076-3425/16/1/76
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