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CIINE Reflects Collagenase-Specific CII Breakdown in Cartilage Explant and Whole Body of Canine

To evaluate collagenase inhibitors for the treatment of osteoarthritis and to correlate them with clinical pathology, canine cartilage explant and anterior cruciate ligament transection (ACLT) models were examined by quantifying the CII neoepitope (CIINE). This peptide is a putative marker for colla...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Satoko Matsukawa, Miki Tanimura, Tomoko Toyosaki-Maeda, Akihiro Noda, Mika Kobayashi, Akira Yamauchi, Junji Onoda, Toshinaga Tsuji, Tatsuya Takahashi, Yoshiyuki Matsuo, Naoshi Fukui
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publishing 2013-01-01
Schriftenreihe:Biomarker Insights
Online-Zugang:https://doi.org/10.4137/BMI.S11627
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