Código QR (código de barras bidimensional)

Liquorice Extract and 18β-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation

Misuse of pyrrolizidine alkaloid (PA)-containing plants or consumption of PA-contaminated foodstuffs causes numerous poisoning cases in humans yearly, while effective therapeutic strategies are still limited. PA-induced liver injury was initiated by cytochrome P450 (CYP)-mediated metabolic activatio...

ver descrição completa

Na minha lista:
Principais autores: Zhangting Wang, Jiang Ma, Sheng Yao, Yisheng He, Kai-Kei Miu, Qingsu Xia, Peter P. Fu, Yang Ye, Ge Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-03-01
coleção:Frontiers in Pharmacology
Assuntos:
18β-glycyrrhetinic acid
pyrrolizidine alkaloid
cytochrome P450
metabolic activation
competitive inhibition
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.850859/full
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados