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The Escherichia coli AZY operon links copper uptake to antibiotic resistance

Abstract Copper import to the bacterial cytoplasm has been underinvestigated as bacterial cuproenzymes are extracytoplasmic. However, copper must access the cytoplasm to interact with metal-dependent transcription factors. In particular, the multiple drug antibiotic resistance (mar) operon is induce...

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Bibliografische Detailangaben
Hauptverfasser: Caitlin D. Palmer, Yara Ghnamah, Nurit Livnat-Levanon, Oded Lewinson, Amy C. Rosenzweig
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-03-01
Schriftenreihe:Communications Biology
Online-Zugang:https://doi.org/10.1038/s42003-025-07884-5
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