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The Escherichia coli AZY operon links copper uptake to antibiotic resistance

Abstract Copper import to the bacterial cytoplasm has been underinvestigated as bacterial cuproenzymes are extracytoplasmic. However, copper must access the cytoplasm to interact with metal-dependent transcription factors. In particular, the multiple drug antibiotic resistance (mar) operon is induce...

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Hlavní autoři: Caitlin D. Palmer, Yara Ghnamah, Nurit Livnat-Levanon, Oded Lewinson, Amy C. Rosenzweig
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-03-01
Edice:Communications Biology
On-line přístup:https://doi.org/10.1038/s42003-025-07884-5
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