Caspase-Mediated Cleavage of the Transcription Factor Sp3: Possible Relevance to Cancer and the Lytic Cycle of Kaposi’s Sarcoma-Associated Herpesvirus

ABSTRACT The open reading frame 50 (ORF50) protein of Kaposi’s sarcoma-associated herpesvirus (KSHV) is the master regulator essential for initiating the viral lytic cycle. Previously, we have demonstrated that the ORF50 protein can cooperate with Sp3 to synergistically activate a set of viral and c...

Descripción completa

Detalles Bibliográficos

Autores principales:	Li-Yu Chen, Lee-Wen Chen, Chien-Hui Hung, Chun-Liang Lin, Shie-Shan Wang, Pey-Jium Chang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology 2022-02-01
Colección:	Microbiology Spectrum
Materias:	KSHV Sp3 ORF50 caspases proteolytic cleavage synergistic activation
Acceso en línea:	https://journals.asm.org/doi/10.1128/spectrum.01464-21
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!