Integrative RNA-seq and iRIP-seq analysis links SNRPA overexpression to transcriptomic and splicing alterations in hepatocellular carcinoma cells
BackgroundSmall Nuclear Ribonucleoprotein Polypeptide A (SNRPA), an RNA-binding protein associated with HCC survival, emerges as a key regulator requiring mechanistic study.MethodsTo delineate SNRPA’s functions, we generated SNRPA-overexpressing HepG2 cells and performed RNA-seq to identify SNRPA-re...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
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Frontiers Media S.A.
2026-05-01
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| Edice: | Frontiers in Oncology |
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| On-line přístup: | https://www.frontiersin.org/articles/10.3389/fonc.2026.1800728/full |
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