Importance of pharmacogenetic markers in the methylenetetrahydrofolate reductase gene during methotrexate treatment in pediatric patients with acute lymphoblastic leukemia

Despite remarkable progress in survival of children with acute lymphoblastic leukemia (ALL) which has reached about 85%, early toxicity and relapse rate remain issues that need to to be resolved. Genetic variants are important factors influencing the metabolism of cytotoxic drugs in ALL tre...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Lazić Jelena, Kotur Nikola, Krstovski Nada, Dokmanović Lidija, Zukić Branka, Predojević-Samardžić Jelica, Životić Maja, Milošević Goran, Đorić Milica, Janić Dragana, Pavlović Sonja
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	University of Belgrade, University of Novi Sad 2017-01-01
Sarja:	Archives of Biological Sciences
Aiheet:	pharmacogenetic markers pediatric lymphoblastic leukemia MTHFR c.677 MTHFR c.1298
Linkit:	http://www.doiserbia.nb.rs/img/doi/0354-4664/2017/0354-46641600091L.pdf
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