Prenatal treprostinil reduces the pulmonary hypertension phenotype in the rat model of congenital diaphragmatic hernia

Summary: Background: Persistent pulmonary hypertension (PH) causes significant mortality and morbidity in infants with congenital diaphragmatic hernia (CDH). Since pulmonary vascular abnormalities in CDH develop early during foetal development, we hypothesized that prenatal maternal administration...

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Hlavní autoři:	Felix Rafael De Bie, Christopher Gates Halline, Travis Kotzur, Kevin Hayes, Christopher Copeland Rouse, Jonathan Chang, Abby Christine Larson, Sameer Ahmad Khan, Ashley Spina, Samantha Tilden, Francesca Maria Russo, Holly Lee Hedrick, Jan Deprest, Emily Anne Partridge
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-07-01
Edice:	EBioMedicine
Témata:	Congenital diaphragmatic hernia Foetal therapy Treprostinil Remodulin
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2352396422002870
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