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MERS-CoV RBD-mRNA vaccine induces potent and broadly neutralizing antibodies with protection against MERS-CoV infection

Middle East respiratory syndrome coronavirus (MERS-CoV), a highly pathogenic coronavirus in the same Betacoronavirus genus and Coronaviridae family as SARS-CoV-2, continues to post a threat to human health. Mortality remains high; therefore, there is a need to develop effective vaccines to prevent M...

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Principais autores: Wanbo Tai, Jian Zheng, Xiujuan Zhang, Juan Shi, Gang Wang, Xiaoqing Guan, Jiang Zhu, Stanley Perlman, Lanying Du
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-09-01
Serier:Virus Research
Fag:
Coronavirus
MERS-CoV
Spike protein
Receptor-binding domain
mRNA vaccine
Neutralizing antibody, Protection
Online adgang:http://www.sciencedirect.com/science/article/pii/S0168170223001181
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