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Transdermal pilocarpine on the skin over salivary glands to increase salivation: an in vivo study

Abstract Background Hyposalivation is treated using oral cholinergic drugs; however, systemic side effects occasionally lead to discontinuation of treatment. We aimed to investigate the effects of transdermal pilocarpine on the salivary gland skin on saliva secretion and safety in rats. Methods Pilo...

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Autori principali: Natsuko Ishida, Ayano Katsura, Koichi Takagaki, Hiroshi Arakawa, Tsutomu Shimada, Satoshi Mizuno, Yoshimichi Sai, Yukio Kato, Hiroyuki Nakamura, Yukio Suga, Ryo Matsushita
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2024-08-01
Serie:BMC Oral Health
Soggetti:
Cholinergic agonist
Hyposalivation
Saliva
Safety
Sweating
Transdermal formulation
Accesso online:https://doi.org/10.1186/s12903-024-04667-y
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