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Depth-corrected multi-factor dissection of chromatin accessibility for scATAC-seq data with PACS

Abstract Single cell ATAC-seq (scATAC-seq) experimental designs have become increasingly complex, with multiple factors that might affect chromatin accessibility, including genotype, cell type, tissue of origin, sample location, batch, etc., whose compound effects are difficult to test by existing m...

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Autors principals: Zhen Miao, Jianqiao Wang, Kernyu Park, Da Kuang, Junhyong Kim
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-01-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-024-55580-5
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