Association between perivascular diffusion and white matter microstructural integrity, free water, Aβ burden, and cognition: diffusion tensor vs. kurtosis tensor

BackgroundPerivascular diffusion holds great potential for the non-invasive assessment of the glymphatic system (GS). However, Gaussian model-based diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) is limited by microstructural alterations. This study aimed to compare cross-s...

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Bibliografische Detailangaben

Hauptverfasser:	Zhiming Zeng, Xin Jia, Shushu Han, Cuidie Zeng, Jing Bi, Lingchen Liu, Yueming Wu, Tengao Gao, Lei Liang, Fangxiao Cheng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-03-01
Schriftenreihe:	Frontiers in Aging Neuroscience
Schlagworte:	cognitive impairment diffusion along the perivascular space free water peak width of skeletonized mean diffusivity trajectory patterns
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fnagi.2026.1733820/full
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