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X-linked inhibitor of apoptosis protein (XIAP) predicts disease-free survival in BRAFV600E mutant papillary thyroid carcinoma in middle eastern patients

BackgroundX-linked inhibitor of apoptosis (XIAP) is the most potent caspase inhibitory IAP family member and its over-expression is implicated in aggressive behavior of various solid tumors, including papillary thyroid carcinoma (PTC). BRAFV600E mutation is the most common oncogenic event in PTC and...

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Principais autores: Sandeep Kumar Parvathareddy, Abdul K. Siraj, Rong Bu, Kaleem Iqbal, Maha Al-Rasheed, Wael Al-Haqawi, Padmanaban Annaiyappanaidu, Nabil Siraj, Saeeda O. Ahmed, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-12-01
coleção:Frontiers in Endocrinology
Assuntos:
papillary thyroid carcinoma
XIAP
BRAFV600E
disease-free survival
prognosis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fendo.2022.1054882/full
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