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Genetic lesions in MYC and STAT3 drive oncogenic transcription factor overexpression in plasmablastic lymphoma

Plasmablastic lymphoma mutational profile is undescribed. Here we performed a targeted exonic NGS analysis of 30 plasmablastic lymphoma cases with a B cell lymphoma dedicated panel and FISH for the detection of MYC rearrangements. A complete phenotyping of the neoplastic and microenvironment cell p...

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Detalles Bibliográficos
Principais autores: Julia Garcia-Reyero, Nerea Martinez Magunacelaya, Sonia Gonzalez de Villambrosia, Sanam Loghavi, Angela Gomez Mediavilla, Raul Tonda, Sergi Beltran, Marta Gut, Ainara Pereña Gonzalez, Emanuele d'Ámore, Carlo Visco, Joseph D. Khoury, Santiago Montes-Moreno
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2020-04-01
Series:Haematologica
Acceso en liña:https://haematologica.org/article/view/9710
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