Sodium Channel Remodeling in Subcellular Microdomains of Murine Failing Cardiomyocytes

BackgroundCardiac sodium channel (NaV1.5) dysfunction contributes to arrhythmogenesis during pathophysiological conditions. Nav1.5 localizes to distinct subcellular microdomains within the cardiomyocyte, where it associates with region‐specific proteins, yielding complexes whose function is location...

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Váldodahkkit:	Mathilde R. Rivaud, Esperanza Agullo‐Pascual, Xianming Lin, Alejandra Leo‐Macias, Mingliang Zhang, Eli Rothenberg, Connie R. Bezzina, Mario Delmar, Carol Ann Remme
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Wiley 2017-12-01
Ráidu:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Fáttát:	heart failure imaging microdomains microscopy Na+ current patch‐clamp
Liŋkkat:	https://www.ahajournals.org/doi/10.1161/JAHA.117.007622
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