Clonally Focused Public and Private T Cells in Resected Brain Tissue From Surgeries to Treat Children With Intractable Seizures

Using a targeted transcriptomics approach, we have analyzed resected brain tissue from a cohort of 53 pediatric epilepsy surgery cases, and have found that there is a spectrum of involvement of both the innate and adaptive immune systems as evidenced by the differential expression of immune-specific...

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Detalhes bibliográficos

Principais autores:	Julia W. Chang, Samuel D. Reyes, Emmanuelle Faure-Kumar, Sandi K. Lam, Michael W. Lawlor, Richard J. Leventer, Sean M. Lew, Paul J. Lockhart, Kathryn Pope, Howard L. Weiner, Noriko Salamon, Harry V. Vinters, Gary W. Mathern, Aria Fallah, Geoffrey C. Owens
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-04-01
coleção:	Frontiers in Immunology
Assuntos:	T cell receptor epilepsy Rasmussen encephalitis focal cortical dysplasia tuberous sclerosis complex
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.664344/full
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