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Differential microglial responses to structurally distinct alpha-synuclein polymorphs

Abstract Synucleinopathies are age-related neurological disorders which include dementia with Lewy bodies (DLB), Parkinson’s disease (PD), and multiple system atrophy (MSA). A hallmark of these diseases is the pathological accumulation of α-synuclein aggregates, along with sustained neuroinflammator...

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Principais autores: Katherine Chang, Jina Kim, Michiyo Iba, Jae-Hyeon Park, Alexandria Beilina, Zulfeqhar A. Syed, Valentina Baena, Liam Horan-Portelance, Mark R. Cookson, Sungyong You, Changyoun Kim
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-12-01
Colecção:Molecular Brain
Acesso em linha:https://doi.org/10.1186/s13041-025-01256-0
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