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Origin of M2 Mϕ and its macrophage polarization by TGF-β in a mice intervertebral injury model

Introduction Studies have identified the presence of M1 and M2 macrophages (Mϕ) in injured intervertebral discs (IVDs). However, the origin and polarization-regulatory factor of M2 Mϕ are not fully understood. TGF-β is a regulatory factor for M2 polarization in several tissues. Here, we investigated...

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Bibliografische gegevens
Hoofdauteurs: Ayumu Kawakubo, Masayuki Miyagi, Yuji Yokozeki, Mitsufumi Nakawaki, Shotaro Takano, Masashi Satoh, Makoto Itakura, Gen Inoue, Masashi Takaso, Kentaro Uchida
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publishing 2022-05-01
Reeks:International Journal of Immunopathology and Pharmacology
Online toegang:https://doi.org/10.1177/03946320221103792
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