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Reduced Airway Hyperresponsiveness by Phosphodiesterase 3 and 4 Inhibitors in Guinea-Pigs

The aim of the present study was to compare the effects of selective phosphodiesterase (PDE) 3, 4 and 5 inhibitors on antigen-induced airway hyperresponsiveness in sensitized guinea-pigs. When the sensitized guinea-pigs were orally pre-treated with the selective PDE4 inhibitor, Ro 20-1724 (30 mg/kg)...

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Hlavní autoři: Nöella Germain, Elisabeth Boichot, Jean-Michel Planquois, Vincent Lagente
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 1999-01-01
Edice:Mediators of Inflammation
Témata:
On-line přístup:http://dx.doi.org/10.1080/09629359990487
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