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Glucuronidation Pathways of 5- and 7-Hydroxypropranolol: Determination of Glucuronide Structures and Enzyme Selectivity

Propranolol, a non-selective beta-blocker medication, has been utilized in the treatment of cardiovascular diseases for several decades. Its hydroxynaphthyl metabolites have been recognized to possess varying degrees of beta-blocker activity due to the unaltered side-chain. This study achieved the s...

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Bibliografiske detaljer
Principais autores: Fan Yang, Maxi Wenzel, Matthias Bureik, Maria Kristina Parr
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-11-01
Serier:Molecules
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Online adgang:https://www.mdpi.com/1420-3049/28/23/7783
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