Higher levels of myelin are associated with higher resistance against tau pathology in Alzheimer’s disease

Abstract Background In Alzheimer’s disease (AD), fibrillar tau initially occurs locally and progresses preferentially between closely connected regions. However, the underlying sources of regional vulnerability to tau pathology remain unclear. Previous brain-autopsy findings suggest that the myelin...

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Prif Awduron:	Anna Rubinski, Nicolai Franzmeier, Anna Dewenter, Ying Luan, Ruben Smith, Olof Strandberg, Rik Ossenkoppele, Martin Dichgans, Oskar Hansson, Michael Ewers, the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2022-09-01
Cyfres:	Alzheimer’s Research & Therapy
Pynciau:	Myelin Myelin water fraction Tau-PET Amyloid-PET Alzheimer’s disease Tau spreading
Mynediad Ar-lein:	https://doi.org/10.1186/s13195-022-01074-9
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