Bayesian ¹³C-Metabolic Flux Analysis of Parallel Tracer Experiments in Granulocytes: A Directional Shift within the Non-Oxidative Pentose Phosphate Pathway Supports Phagocytosis

The pentose phosphate pathway (PPP) plays a key role in the cellular regulation of immune function; however, little is known about the interplay of metabolic adjustments in granulocytes, especially regarding the non-oxidative PPP. For the determination of metabolic mechanisms within glucose metaboli...

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Principais autores:	Melanie Hogg, Eva-Maria Wolfschmitt, Ulrich Wachter, Fabian Zink, Peter Radermacher, Josef Albert Vogt
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-12-01
Series:	Metabolites
Assuntos:	Bayesian modeling gas chromatography–mass spectrometry glucose metabolism immunometabolism isotopic tracer mass isotopomer distribution analysis
Acceso en liña:	https://www.mdpi.com/2218-1989/14/1/24
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