Impacts of ABCG2 loss of function variant (p. Gln141Lys, c.421 C > A, rs2231142) on lipid levels and statin efficiency: a systematic review and meta-analysis

Abstract Background The latest evidence indicates that ATP-binding cassette superfamily G member 2 (ABCG2) is critical in regulating lipid metabolism and mediating statin or cholesterol efflux. This study investigates whether the function variant loss within ABCG2 (rs2231142) impacts lipid levels an...

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Үндсэн зохиолчид:	Yang Liu, Yuan Chen, Baozhu Wei, Hang Li, Yuanyuan Peng, Zhi Luo
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2024-04-01
Цуврал:	BMC Cardiovascular Disorders
Нөхцлүүд:	ABCG2 rs2231142 Dyslipidemia Statin Coronary artery disease
Онлайн хандалт:	https://doi.org/10.1186/s12872-024-03821-2
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!