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The small non-coding RNA B11 regulates multiple facets of Mycobacterium abscessus virulence.

Mycobacterium abscessus causes severe disease in patients with cystic fibrosis. Little is known in M. abscessus about the roles of small regulatory RNAs (sRNA) in gene regulation. We show that the sRNA B11 controls gene expression and virulence-associated phenotypes in this pathogen. B11 deletion fr...

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Príomhchruthaitheoirí: Michal Bar-Oz, Maria Carla Martini, Maria Natalia Alonso, Michal Meir, Nicola Ivan Lore, Paolo Miotto, Camilla Riva, Shiva K Angala, Junpei Xiao, Catherine S Masiello, Maria-Anna Misiakou, Huaming Sun, Justin K Moy, Mary Jackson, Helle Krogh Johansen, Daniela Maria Cirillo, Scarlet S Shell, Daniel Barkan
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2023-08-01
Sraith:PLoS Pathogens
Rochtain ar líne:https://doi.org/10.1371/journal.ppat.1011575
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