<italic toggle="yes">Plasmodium falciparum</italic> K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness <italic toggle="yes">In Vitro</italic>

ABSTRACT The emergence and spread in Southeast Asia of Plasmodium falciparum resistance to artemisinin (ART) derivatives, the cornerstone of first-line artemisinin-based combination therapies (ACTs), underscore the urgent need to identify suitable replacement drugs. Discovery and development efforts...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Judith Straimer, Nina F. Gnädig, Barbara H. Stokes, Michelle Ehrenberger, Audrey A. Crane, David A. Fidock
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology 2017-05-01
Serija:	mBio
Teme:	K13/Kelch13 Plasmodium falciparum artemisinin drug resistance fitness gene editing
Online dostop:	https://journals.asm.org/doi/10.1128/mBio.00172-17
Oznake:	Označite Brez oznak, prvi označite!