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Carbohydrate-Small Molecule Hybrids as Lead Compounds Targeting IL-6 Signaling

In the past 25 years, a number of efforts have been made toward the development of small molecule interleukin-6 (IL-6) signaling inhibitors, but none have been approved to date. Monosaccharides are a diverse class of bioactive compounds, but thus far have been unexplored as a scaffold for small mole...

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Principais autores: Daniel C. Schultz, Li Pan, Tiffany Wang, Conner Booker, Iram Hyder, Laura Hanold, Garret Rubin, Yousong Ding, Jiayuh Lin, Chenglong Li
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2023-01-01
סדרה:Molecules
נושאים:
Interleukin-6
structure-based drug design
docking
carbohydrate
גישה מקוונת:https://www.mdpi.com/1420-3049/28/2/677
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