Characterization of highly frequent epitope-specific CD45RA⁺/CCR7^+/-T lymphocyte responses against p53-binding domains of the human polyomavirus BK large tumor antigen in HLA-A*0201+ BKV-seropositive donors

<p>Abstract</p> <p>Human polyomavirus BK (BKV) has been implicated in oncogenic transformation. Its ability to replicate is determined by the binding of its large tumor antigen (LTag) to products of tumor-suppressor genes regulating cell cycle, as specifically p53. We investigated CD8+ T immune resp...

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Manylion Llyfryddiaeth

Prif Awduron:	Zajac Paul, Gosert Rainer, Sais Giovanni, Hudolin Tvrtko, Wyler Stephen, Bracci Laura, Provenzano Maurizio, Palu' Giorgio, Heberer Michael, Hirsch Hans H, Spagnoli Giulio C
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2006-11-01
Cyfres:	Journal of Translational Medicine
Mynediad Ar-lein:	http://www.translational-medicine.com/content/4/1/47
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!