Tri-ortho-cresyl phosphate induces hepatic steatosis by mTOR activation and ER stress induction

Tri-ortho-cresyl phosphate (TOCP), an organophosphorus compound (OP), which is widely used as plasticizer, flame retardant and other industrial products, has been reported to cause multiple toxicities including neurotoxicity and reproductive toxicity. However, it remains to be elusive whether TOCP i...

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Bibliografische Detailangaben

Hauptverfasser:	Jing Li, Yi-Jun Wu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2024-02-01
Schriftenreihe:	Ecotoxicology and Environmental Safety
Schlagworte:	Organophosphorus compound Endoplasmic reticulum stress MTOR SREBPs Hepatic steatosis Rapamycin
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S014765132400085X
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