The mitochondria-targeted derivative of the classical uncoupler of oxidative phosphorylation carbonyl cyanide m-chlorophenylhydrazone is an effective mitochondrial recoupler.

The synthesis of a mitochondria-targeted derivative of the classical mitochondrial uncoupler carbonyl cyanide-m-chlorophenylhydrazone (CCCP) by alkoxy substitution of CCCP with n-decyl(triphenyl)phosphonium cation yielded mitoCCCP, which was able to inhibit the uncoupling action of CCCP, tyrphostin...

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Váldodahkkit:	Iliuza R Iaubasarova, Ljudmila S Khailova, Alexander M Firsov, Vera G Grivennikova, Roman S Kirsanov, Galina A Korshunova, Elena A Kotova, Yuri N Antonenko
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Public Library of Science (PLoS) 2020-01-01
Ráidu:	PLoS ONE
Liŋkkat:	https://doi.org/10.1371/journal.pone.0244499
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