<i>TERT</i> Promoter Mutations Increase Sense and Antisense Transcription from the <i>TERT</i> Promoter

<b>Background:</b> Chief among mechanisms of telomerase reverse transcriptase (TERT) reactivation is the appearance of mutations in the <i>TERT</i> promoter. The two main <i>TERT</i> promoter mutations are C>T transitions located −146C>T and −124C>T upstream from the translational start site. They g...

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Prif Awduron:	François Hafezi, Lisa Jaxel, Morgane Lemaire, Jonathan D. Turner, Danielle Perez-Bercoff
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2021-11-01
Cyfres:	Biomedicines
Pynciau:	<i>TERT</i> promoter mutations Telomerase TERT <i>TERT</i> transcription bidirectional promoter lncRNA <i>TAPAS</i>
Mynediad Ar-lein:	https://www.mdpi.com/2227-9059/9/12/1773
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!