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Mendelian Randomization Integrating GWAS, eQTL, and mQTL Data Identified Genes Pleiotropically Associated With Atrial Fibrillation

Background: Atrial fibrillation (AF) is the most common arrhythmia. Genome-wide association studies (GWAS) have identified more than 100 loci associated with AF, but the underlying biological interpretation remains largely unknown. The goal of this study is to identify gene expression and DNA methyl...

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Principais autores: Yaozhong Liu, Biao Li, Yingxu Ma, Yunying Huang, Feifan Ouyang, Qiming Liu
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cardiovascular Medicine
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fcvm.2021.745757/full
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