Case Report: Systemic amyloidosis unmasked by progressive hepatomegaly after splenectomy for non-traumatic spleen rupture in a patient with chronic liver disease

BackgroundNon-traumatic splenic rupture (NSR) is a rare manifestation of systemic amyloid light-chain amyloidosis (AL amyloidosis), a plasma cell dyscrasia best known for its cardiorenal involvement. This case is unique because the diagnostic clue from NSR was initially overlooked until the underlyi...

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Principais autores:	Li-Ping Sheng, Ya-Yun Zhang, Ming Zhang, Bo-Zhi Lin, Rui-Fang Ma, Li-Na Han, Hui Liu, Feng-Qin Hou, Gui-Qiang Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-04-01
Colecção:	Frontiers in Medicine
Assuntos:	amyloidosis daratumumab hepatomegaly missed diagnosis splenic rupture
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1807002/full
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