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CRISPR/Cas9-Mediated Gene Correction in Osteopetrosis Patient-Derived iPSCs

Background: Osteopetrosis represents a rare genetic disease with a wide range of clinical and genetic heterogeneity, which results from osteoclast failure. Although up to 10 genes have been identified to be related with osteopetrosis, the pathogenesis of osteopetrosis remains foggy. Disease-specific...

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Bibliografische gegevens
Hoofdauteurs: Dandan Li, Minglin Ou, Wei Zhang, Qi Luo, Wanxia Cai, Chune Mo, Wenken Liang, Guandong Dai, Lianghong Yin, Peng Zhu, Donge Tang, Yong Dai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: IMR Press 2023-06-01
Reeks:Frontiers in Bioscience-Landmark
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Online toegang:https://www.imrpress.com/journal/FBL/28/6/10.31083/j.fbl2806131
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