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Biofabrication of prevascularized spheroids for bone tissue engineering by fusion of microvascular fragments with osteoblasts

IntroductionSpheroids are promising building blocks for scaffold-free bone tissue engineering. Their rapid vascularization is of major importance to guarantee their survival after transplantation. To achieve this, we herein introduce the biofabrication of prevascularized spheroids by fusion of adipo...

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Principais autores: Selina Wrublewsky, Jessica Schultz, Tekoshin Ammo, Caroline Bickelmann, Wolfgang Metzger, Thomas Später, Tim Pohlemann, Michael D. Menger, Matthias W. Laschke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-09-01
coleção:Frontiers in Bioengineering and Biotechnology
Assuntos:
microvascular fragments
osteoblasts
spheroid
bone
tissue engineering
vascularization
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1436519/full
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