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Triptolide improves microbial dysbiosis and metabolite disorder in db/db mice

Background Diabetic kidney disease (DKD) is an increasing global public health problem. Triptolide (TP) has a good therapeutic effect on DKD and is widely used in China. However, the mechanism of TP is still unclear.Methods Db/db mice models were subjected to TP for 12 weeks. UHPLC-QE-MS and 16S rRN...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Lingfei Lu, Yixin Li, Yanyan Zhou, Jiwei Chen, Tian Fu, Jiamei Zhuang, Hongcheng Peng, Fang Liu, Linlin Sun, Jiandong Lu, Guoliang Xiong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2025-12-01
Schriftenreihe:Renal Failure
Schlagworte:
Diabetic kidney disease
Traditional Chinese Medicine
Triptolide
Metabolome
Microbiome
Online-Zugang:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2552913
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