PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome

BackgroundWe performed a transcriptomic analysis of adrenal signaling pathways in various forms of endogenous Cushing’s syndrome (CS) to define areas of dysregulated and druggable targets.MethodologyNext-generation sequencing was performed on adrenal samples of patients with primary bilateral macron...

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Detaylı Bibliyografya
Asıl Yazarlar:	Sharmilee Vetrivel, Mariangela Tamburello, Andrea Oßwald, Ru Zhang, Ali Khan, Sara Jung, Jessica E. Baker, William E. Rainey, Elisabeth Nowak, Barbara Altieri, Mario Detomas, Deepika Watts, Tracy Ann Williams, Ben Wielockx, Felix Beuschlein, Martin Reincke, Silviu Sbiera, Anna Riester
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2023-11-01
Seri Bilgileri:	Frontiers in Endocrinology
Konular:	transcriptome hypercortisolism rosiglitazone adrenocortical cell line steroidome cortisol
Online Erişim:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1265794/full
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PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome

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