Synthesis of RP 48497, an Impurity of Eszopiclone
Abstract: RP 48497 is a photodegradation product of eszopiclone, a non-benzodiazepine sedative-hypnotic used in the treatment of insomnia. We report herein the first synthesis of RP 48497 via reduction, chlorination, and recyclization of 6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydropyrrolo[3,4-b]py...
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| Principais autores: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI AG
2008-08-01
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| 叢編: | Molecules |
| 主題: | |
| 在線閱讀: | http://www.mdpi.com/1420-3049/13/8/1817/ |
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