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Comparative Geometrical Analysis of Leucine-Rich Repeat Structures in the Nod-Like and Toll-Like Receptors in Vertebrate Innate Immunity

The NOD-like receptors (NLRs) and Toll-like receptors (TLRs) are pattern recognition receptors that are involved in the innate, pathogen pattern recognition system. The TLR and NLR receptors contain leucine-rich repeats (LRRs) that are responsible for ligand interactions. In LRRs short β-strands sta...

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Principais autores: Norio Matsushima, Hiroki Miyashita, Purevjav Enkhbayar, Robert H. Kretsinger
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2015-08-01
Serier:Biomolecules
Fag:
TLRs
NLRs
receptor
RP105
CD14
helix
dimer
Online adgang:http://www.mdpi.com/2218-273X/5/3/1955
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