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Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice.

The Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency characterized by recurrent infections, thrombocytopenia, eczema, and high incidence of malignancy and autoimmunity. The cellular mechanisms underlying autoimmune complications in WAS have been extensively studied; however...

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Principais autores: Tadafumi Yokoyama, Ayumi Yoshizaki, Karen L Simon, Martha R Kirby, Stacie M Anderson, Fabio Candotti
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Acceso en liña:https://doi.org/10.1371/journal.pone.0139729
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