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Transcriptomic signatures of the insular cortex in a mouse model of neuropathic pain

BackgroundNeuropathic pain (NP) remains poorly managed by current therapies. Although the insular cortex (IC) is critical for cortical pain processing, a comprehensive spatiotemporal molecular characterization of the IC in NP is lacking.MethodsWe employed RNA sequencing of the anterior (aIC) and pos...

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Principais autores: Yang Bai, Guo-Quan Yao, Cheng-Guo Jiang, Chong Zhang, Yu-Gang Diao, Si-Zhe Feng, Guo-Biao Liang, Xin-Tong Qiu, Wei Jiang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-07-01
Serier:Frontiers in Molecular Neuroscience
Fag:
insular cortex
neurodegenerative disease
neuropathic pain
synaptic plasticity
transcriptomics
Online adgang:https://www.frontiersin.org/articles/10.3389/fnmol.2026.1840950/full
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