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Single‐Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

ABSTRACT Purpose After traumatic brain injury (TBI), ischemia and hypoxia of brain tissue, glucose undergoes anaerobic fermentation, leading to a large accumulation of lactic acid. Our aim was to explore the role of lactate metabolism in brain cells after TBI. Method In scRNA‐seq dataset, 10‐week‐ol...

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Principais autores: Zhang Bu, Yuqian Zhou, Feng Xu, Shan Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2025-05-01
coleção:Brain and Behavior
Assuntos:
astrocytes
lactate metabolism
traumatic brain injury
Acesso em linha:https://doi.org/10.1002/brb3.70428
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