Single-cell RNA sequencing and proteomics uncover SIRPα-CD47 immune checkpoint and glycolysis-driven immune evasion in cardiac myxoma

Cardiac myxoma (CM), a rare primary cardiac tumor, poses significant life-threatening risks. Current CM research has remained largely limited to clinical case observations and pathological analyses, thus restricting its clinical therapeutic impact. Fundamental research should be urgently strengthene...

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Autors principals:	Xinyuan Zhu, Qingle Gao, Xintong Dai, Baofa Sun, Yanping Li, Hongyan Zhai, Changliang Shan
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-09-01
Col·lecció:	Frontiers in Immunology
Matèries:	single-cell sequencing immune microenvironment glycolysis immune evasion M2 polarization IL-10
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1652645/full
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