Modeling hypercholesterolemia and vascular lipid accumulation in LDL receptor mutant zebrafish
Elevated plasma LDL cholesterol is the dominant risk factor for the development of atherosclerosis and cardiovascular disease. Deficiency in the LDL receptor (LDLR) is a major cause of familial hypercholesterolemia in humans, and the LDLR knockout mouse is a major animal model of atherosclerosis. He...
Gardado en:
| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2018-02-01
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| Series: | Journal of Lipid Research |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S0022227520342413 |
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