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Unexpected reaction of “wild-type” gastrointestinal stromal tumor to imatinib: case report and literature review

BackgroundMost of gastrointestinal stromal tumors (GISTs) are driven by mutations in the KIT/PDGFRA genes and can benefit from TKIs treatment. However, a small subset of GIST (10%-15%) are called “wild-type” GISTs due to the lack of these mutations. Theoretically, they would not benefit from TKIs tr...

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Détails bibliographiques
Auteurs principaux: Yang He, Mingxu Da, Chuanlei Fan, Pengxian Tao
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2024-01-01
Collection:Frontiers in Oncology
Sujets:
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fonc.2023.1334784/full
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