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Safety and Efficacy of Matrix-Associated Autologous Chondrocyte Implantation With Spheroids for Patellofemoral or Tibiofemoral Defects: A 5-Year Follow-up of a Phase 2, Dose-Confirmation Trial

Background: Matrix-associated autologous chondrocyte implantation (ACI) is a well-established treatment for cartilage defects. High-level evidence at midterm follow-up is limited, especially for ACI using spheroids (spherical aggregates of ex vivo expanded human autologous chondrocytes and self-synt...

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Bibliografiske detaljer
Principais autores: Arnd Hoburg MD, Philipp Niemeyer MD, PhD, Volker Laute MD, Wolfgang Zinser MD, Thilo John MD, Christoph Becher MD, PhD, Kaywan Izadpanah MD, Peter Diehl MD, PhD, Thomas Kolombe MD, Jakob Fay MD, Rainer Siebold MD, PhD, Stefan Fickert MD, PhD
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publishing 2022-01-01
Serier:Orthopaedic Journal of Sports Medicine
Online adgang:https://doi.org/10.1177/23259671211053380
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